Licorice PDRN  (Liquid) are highactivity natural plant extracellular vesicles extracted from fresh Glycyrrhiza glabra L. (Licorice ) using lowtemperature bioseparation, ultracentrifugation and purification technology. They retain natural active ingredients including glabridin, glycyrrhizic acid, flavonoids, polysaccharides, PDRN, endogenous miRNAs and functional proteins, fully complying with cosmetic grade, highend functional raw material grade and international cosmetic ingredient quality standards. As a biomimetic skinfriendly active substance with high transdermal permeability, they feature excellent brightening, antiinflammatory, soothing, antioxidant and barrier repair properties, good biocompatibility, nonirritating and nonsensitizing. They are widely used in highend skincare, postprocedure repair, sensitive skin care, pigment brightening and mild daily care markets