Polydeoxyribonucleotide (PDRN) has emerged as the "Gold Standard" in regenerative aesthetics. Extracted from salmon sperm DNA—chosen for its 95% similarity to human DNA—PDRN is not merely an anti-aging ingredient; it is a bio-stimulator that triggers DNA synthesis and cellular repair at the mitochondrial level.
PDRN acts through the A2A adenosine receptor, stimulating the production of growth factors (VEGF, FGF) and facilitating the regeneration of Type I collagen and elastic fibers. This process significantly shortens healing times for damaged skin.
Our Medical Grade PDRN undergoes rigorous enzymatic hydrolysis. We maintain a fragment size between 50 to 1500 base pairs, ensuring optimal bioavailability and minimal immunological risk for injectable and topical applications.
The global PDRN market is projected to grow at a CAGR of 12.5% through 2030. Asia-Pacific currently leads demand, followed by North America, as consumers shift from superficial fillers to cellular-level restorative treatments.
Founded in 2018, Shaanxi Bieyouth Biotech Co., Ltd. has bridged the gap between raw biological resources and high-tech pharmaceutical requirements. As a GMP-certified large-scale gold supplier, we leverage China's industrial infrastructure to provide unprecedented efficiency.
Annual Tonnage Capacity
Quality Control System
Research Breakthroughs
Established Excellence
In South Korea and China, PDRN is the core of "Salmon Injection" treatments. It is used to treat melasma, acne scarring, and general skin rejuvenation by accelerating the "wound healing" response without inflammation.
Clinically used for tendon repair and osteoarthritis management. PDRN reduces inflammation in cartilage and promotes the regeneration of ligament tissue, making it a favorite for sports medicine procurement.
PDRN is being integrated into high-end serums and masks. Its water-solubility and stability make it an ideal active ingredient for OEM brands looking to offer "clinical-grade" home care solutions.
Participated in Shanghai International Cosmetics Raw Materials Exhibition, showcasing next-gen PDRN stability.
Formally obtained FDA registration, expanding our footprint in the North American pharmaceutical market.
Launched global trade operations; established the Biological Research Institute for advanced plant & animal extraction.
Awarded "Integrity Enterprise" and "Quality Assured Enterprise" for our commitment to transparent manufacturing.
From raw PDRN powder to finished clinical vials, Shaanxi Bieyouth provides a full-spectrum partnership.
Deep dive into your target market regulations and specific formulation needs (viscosity, concentration, purity).
Our lab creates custom samples. We verify the biological activity using DNA electrophoresis and HPLC testing.
Utilizing our 50,000-ton capacity, we ensure batch-to-batch consistency and rapid lead times.
Medical Grade PDRN requires a higher degree of purification (typically >98%) and specific molecular weight control (50-1500bp). It must be endotoxin-controlled to be safe for intradermal injection, whereas cosmetic grade is optimized for transdermal absorption.
We use a specialized lyophilization (freeze-drying) technique for our bulk powders, which maintains the DNA triple-helix structure even during international shipping. Our PDRN remains stable at room temperature for up to 24 months when sealed.
Yes. Our ODM service includes sterile vial filling, custom labeling, and secondary packaging that meets international medical device aesthetics and standards.
Salmon sperm DNA is remarkably similar to human leukocyte DNA. This minimizes the risk of allergic reactions (low immunogenicity) while providing the high concentration of nucleotides required for effective A2A receptor stimulation.
Penny
Angel Wang
Monica Li
Margaret Zhang
Bieyouth
